BMC Medical Genetics

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Open Access Highly Access Research article

The genetic study of three population microisolates in South Tyrol (MICROS): study design and epidemiological perspectives

Cristian Pattaro1*, Fabio Marroni1, Alice Riegler1, Deborah Mascalzoni1, Irene Pichler1, Claudia B Volpato1, Umberta Dal Cero1, Alessandro De Grandi1, Clemens Egger1, Agatha Eisendle1, Christian Fuchsberger1, Martin Gögele1, Sara Pedrotti1, Gerd K Pinggera1, Stefan A Stefanov1, Florian D Vogl2, Christian J Wiedermann3,4, Thomas Meitinger5,6 and Peter P Pramstaller1,7,8

Author Affiliations

1 Institute of Genetic Medicine, European Academy, Bolzano, Italy

2 Department of Gynaecology, Hospital of Merano, Via Rossini 5, 39012 Merano-Meran, Italy

3 Laboratory of Medical Intensive Care, Division of General Internal Medicine, Department of Medicine, Medical University of Innsbruck, Innsbruck, Austria

4 Division of Internal Medicine II, Department of Medicine, Central Hospital of Bolzano, Bolzano/Bozen, Italy

5 Institute of Human Genetics, Technical University of Munich, Munich, Germany

6 GSF – National Research Center for Environment and Health, Institute of Human Genetics, München-Neuherberg, Germany

7 Department of Neurology, University of Lübeck, Lübeck, Germany

8 Department of Neurology, General Regional Hospital, Bolzano, Italy

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BMC Medical Genetics 2007, 8:29 doi:10.1186/1471-2350-8-29

Published: 5 June 2007

Additional files

Additional file 1:

Distribution of cardiovascular and respiratory traits. Prevalence of the main cardiovascular disease symptoms (upper panel) and respiratory traits (lower panel), by age and sex (solid line = females, dashed line = males), with 95% confidence intervals.

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Additional file 2:

Distribution of cardiovascular disease's determinants. Differential distribution of six quantitative traits by age and sex (males: gray; females: white). Age is reported on the x-axis.

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Additional file 3:

Distribution of liver-related intermediate phenotypes. Distribution of glutamic-oxaloacetic transaminase (GOT), glutamate pyruvate transaminase (GPT) and gamma glutamyl-transpeptidase (GGT), by age and sex (gray = males, white = females).

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