Figure 4.

A novel deletion mutation in the 3' untranslated region of the myostatin gene. A part of the sequencing result for the 3' untranslated region of the myostatin gene is shown. In the control all of the sequences matched with that of the wild-type sequence (Genbank: AC073120), including the repeat of AT dinucleotides (boxes) (control). In the sequence of one DMD case (case 100) the repeat of AT dinucleotides was not present, removing AT dinucleotides at 2264 and 2265^th nucleotide (c.2264-2265delAT) (patient).