Figure 2.

Analysis of APC germline mutations of exon 9. a. Sequencing pattern of alternatively spliced part of the exon 9 (forward) in proband of the family 220 (AFAP phenotype) with heterozygous substitution G>T at nucleotide position 1111 (p.Gly371X) and control b. Sequencing pattern of part in the regularly spliced region of the exon 9 (forward) in proband of the family 202 (FAP phenotype) with heterozygous deletion T at nucleotide position 1251 (p.Cys417TrpfsX37) and control.