|
ADRB3 genotype and BMD: Standardized regression coefficient from the multiple regression analyses |
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| LSBMD |
FNBMD |
|||
|
|
||||
| Coefficient |
P value |
Coefficient |
P value |
|
|
|
||||
| Women |
||||
| Age |
-0.040 |
0.380 |
-0.344 |
<0.01 |
| BMI |
0.366 |
<0.01 |
0.382 |
<0.01 |
| Smoking |
-0.041 |
0.37 |
-0.087 |
0.03 |
| Calcium intake |
-0.018 |
0.69 |
0.050 |
0.23 |
| Physical activity |
0.140 |
<0.01 |
0.035 |
0.40 |
| ADRB3a |
0.044 |
0.33 |
0.046 |
0.26 |
| R2 |
0.162 |
0.302 |
||
|
|
||||
| Men |
||||
| Age |
-0.018 |
0.78 |
-0.187 |
<0.01 |
| BMI |
0.231 |
<0.01 |
0.240 |
<0.01 |
| Smoking |
-0.104 |
0.09 |
-0.149 |
<0.01 |
| Calcium intake |
0.091 |
0.14 |
0.048 |
0.01 |
| Physical activity |
0.124 |
0.05 |
0.036 |
0.43 |
| ADRB3a |
0.001 |
0.99 |
0.003 |
0.60 |
| R2 |
0.074 |
0.120 |
||
|
LSBMD, lumbar spine bone mineral density; FNBMD, femoral neck bone mineral density. R2: coefficient of determination; proportion of variance of BMD (LSBMD or FNBMD) accounted for by all the factors in the model. aNon-Arg allele carrier and Arg allele carrier. | ||||
Wang et al. BMC Medical Genetics 2006 7:57 doi:10.1186/1471-2350-7-57 |
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