Table 1

Characteristics of cultured fibroblasts.

Cell Line
Early Passage
Late Passage



Passage no.
Doubling time (d)
beta-gal % pos.
Passage no.
Doubling time (d)
beta-gal % pos.

DS1
13
2
<1
23
5.5
63.4
DS2
7
1
<1
12
19.5
37.2
DS3
4
2.5
<1
11
9
41.0
DS4
10
1.5
<1
14
8
47.5
DS5
3
5
nd
nd
nd
nd
C1
12
2
<1
24
12
55.5
C2
9
1.5
6.7
15
21
63.3
C3
5
1.5
<1
11
9.5
46.2
C4
10
2.5
<1
14
4.5
34.0
C5
3
2
n.d.
n.d.
n.d.
n.d.
C6
3
5
n.d.
n.d.
n.d.
n.d.

Li et al. BMC Medical Genetics 2006 7:24   doi:10.1186/1471-2350-7-24