Figure 4.

Comparison of the NER capacity of a PBL sample from our BRCA1 mutation carrier patient with those of a population of disease-free controls. The dark horizontal line indicates the average for the normal population, while the dotted lines indicate upper limits for residual NER activity in patients with the hereditary NER deficiency disease XP (0.50) and the cut-off established in our breast tissue study that identified tumors with high sensitivity and specificity (0.70).

Latimer et al. BMC Medical Genetics 2005 6:26   doi:10.1186/1471-2350-6-26
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