Table 3

Pairwise linkage disequilibrium indicated by the D' value (above the diagonal)^a and statistical significance indicated by the p value (below the diagonal)^b for the ten TPH1 SNPs.

T-1721G

A-1067G

G-347T

T3840A

G7465A

A12517C

C18626G

A20004C

C27224T

A27237G

T-1721G

1.000

0.911

0.129

0.834

0.505

0.601

0.726

0.329

0.177

A-1067G

<0.001

0.913

0.076

0.863

0.537

0.655

0.722

0.391

0.274

G-347T

<0.001

<0.001

0.121

0.840

0.450

0.645

0.655

0.447

0.032

T3840A

0.020

0.166

0.033

0.969

0.575

0.870

0.652

0.512

0.574

G7465A

<0.001

<0.001

<0.001

<0.001

0.685

0.711

0.826

0.741

0.929

A12517C

<0.001

<0.001

<0.001

<0.001

<0.001

0.684

0.320

0.663

0.039

C18626G

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

0.765

0.684

0.780

A20004C

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

0.624

0.625

C27224T

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

0.956

A27237G

0.203

0.096

0.840

<0.001

<0.001

0.809

<0.001

<0.001

<0.001

^a Standardized linkage disequlibrium coefficient (absolute D' value) of Lewontin was shown.

^b Significant levels based on the chi-squared distribution to test whether the disequilibrium value differs from zero (one degree of freedom). Bold and underline indicate no significant LD at the p < 0.05 level.

Lai et al. BMC Medical Genetics 2005 6:14   doi:10.1186/1471-2350-6-14