|
Allele average effects αS, αM and αL estimated for S, M and L alleles respectively of the 3'VNTR-APOB polymorphism in the whole sample of healthy subjects after normalization for age, sex and BMI (computed according to the formula: BMI = weight [Kg]/ height [m2]) |
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| αS |
95% c.i. αS |
αM |
95% c.i. αM |
αL |
95% c.i. αL |
|
|
|
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| TC |
-5.98 |
-11.62 ÷ -0.74 |
+1.67 |
-0.28 ÷ +3.90 |
+0.93 |
-6.20 ÷ +8.13 |
| HDL-C |
-0.09 |
-2.01 ÷ +1.71 |
-0.08 |
-0.64 ÷ +0.81 |
+0.26 |
-2.51 ÷ +2.30 |
| LDL-C |
-4.41 |
-8.93 ÷ -0.20 |
+1.28 |
-0.65 ÷ +3.10 |
+0.45 |
-5.70 ÷ +6.82 |
| TG (Log10) |
+0.01 |
-0.02 ÷ +0.03 |
0.00 |
-0.01 ÷ +0.01 |
-0.01 |
-0.04 ÷ +0.02 |
|
TC: serum Total Cholesterol; HDL-C: serum HDL-Cholesterol; LDL-C: serum LDL-Cholesterol; TG: serum Tryglycerides. Average effects are expressed in mg/dL. Confidence intervals (c.i.) are computed by bootstrap (1,000 replications). | ||||||
Garasto et al. BMC Medical Genetics 2004 5:3 doi:10.1186/1471-2350-5-3 |
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