Additional file 5.

Allelic expression analysis in joint tissue from osteoarthritis (OA) patients. Allelic expression was assessed using the transcript single nucleotide polymorphisms (SNPs) (A) rs11177, (B) rs6617, (C) rs17264436, (D) rs6976, (E) rs7639267, (F) rs6769789 and (G) rs747343. Allelic expression of cDNA was normalised to its corresponding DNA. Data is presented as a ratio of expression of the major allele over that of the minor allele; hence a value above 1 means that there is less of the OA-associated allele. Samples are grouped according to the genotype at the OA-associated SNP rs6976, which are shown. Error bars represent the standard error of the mean. FP, fat pad; Sy, synovium; Me, meniscus; Li, ligament.

Format: PDF Size: 56KB Download file

This file can be viewed with: Adobe Acrobat Reader

Gee et al. BMC Medical Genetics 2014 15:53   doi:10.1186/1471-2350-15-53