Table 2

Complete meta-analysis results in European Americans, effect size expressed in terms of % difference in mean BMI
Current smokers Former/never smokers Combined sex and smoking status*
Gene SNP CA sex p-value for interaction % difference in mean BMI (95% CI) p-value N % difference in mean BMI (95% CI) p-value N % difference in mean BMI (95% CI) p-value N AF
MTCH2 rs10838738 G F 0.40 0.6 (-0.4 - 1.51) 0.23 2404 0.4 (-0.2 - 1.11) 0.20 17737 0.51 (0.22 - 0.8) 1.0E-03 34679 0.35
M 0.24 0.3 (-0.5 - 1.11) 0.40 1525 0.8 (0.1 - 1.41) 0.03 4945
GNPDA2 rs10938397 G F 0.87 0.1 (-1.39 - 1.61) 0.88 2165 0.3 (-0.3 - 1.01) 0.28 15961 0.29 (0.004 - 0.69) 0.04 31346 0.43
M 0.63 0.1 (-1 - 1.31) 0.82 1398 0.5 (-0.2 - 1.21) 0.13 3753
KCTD15 rs11084753 G F 0.42 0.8 (0.004 - 1.61) 0.05 3447 −0.1 (-0.7 - 0.4) 0.60 21303 0.11 (-0.18 - 0.4) 6.1E-01 29411 0.67
M 0.46 −0.1 (-0.7 - 0.6) 0.78 2321 0.2 (-0.3 - 0.7) 0.42 7901
MC4R rs12970134 A F 0.30 0.5 (-0.6 - 1.61) 0.38 1619 0.6 (-0.3 - 1.41) 0.20 14992 0.8 (0.29 - 1.2) 1.3E-03 21987 0.26
M 0.64 0.1 (-0.9 - 1.11) 0.85 672 1.11 (-0.3 - 2.53) 0.12 2492
MC4R rs17782313 C F 0.60 0.8 (-0.1 - 1.61) 0.09 3449 0.7 (0.1 - 1.31) 0.02 21334 0.22 (-0.004 - 0.51) 0.08 35398 0.22
M 0.83 0.1 (-0.6 - 0.8) 0.72 2326 0.6 (0.002 - 1.21) 0.05 7930
NEGR1 rs2815752 T F 0.45 0.7 (-0.1 - 1.51) 0.07 3393 0.2 (-0.3 - 0.7) 0.38 20898 0.51 (0.11 - 0.8) 9.2E-03 28261 0.63
M 0.96 0.4 (-0.3 - 1.11) 0.30 2272 0.1 (-0.4 - 0.6) 0.69 7363
TMEM18 rs6548238 C F 0.15 1.11 (0.2 - 2.12) 0.02 3424 1.21 (0.5 - 1.82) 7.0E-04 21261 1.02 (0.62 - 1.42) 8.6E-08 37061 0.83
M 0.69 0.7 (-0.2 - 1.51) 0.12 2290 0.9 (0.2 - 1.51) 0.01 7805
SH2B1 rs7498665 G F 0.47 0.7 (-0.2 - 1.61) 0.11 2400 0.9 (0.3 - 1.51) 6.0E-03 17698 0.22 (-0.11 - 0.62) 2.2E-01 31383 0.38
M 0.49 0.2 (-0.6 - 1.01) 0.67 1530 0.8 (0.1 - 1.51) 0.02 4948
FTO rs9939609 A F 0.08 1.71 (0.9 - 2.53) 3.5E-05 2719 0.6 (-0.01 - 1.11) 0.05 18221 1.31 (1.02 - 1.71) 4.6E-15 28286 0.40
M 0.94 1.31 (0.6 - 1.92) 2.8E-04 1457 1.51 (1.01 - 2.12) 6.9E-08 5671

CA Coded allele, M male, F female, CI confidence interval, AF coded allele frequency.

Fesinmeyer et al.

Fesinmeyer et al. BMC Medical Genetics 2013 14:6   doi:10.1186/1471-2350-14-6

Open Data