The promoter methylation of MUC2 in HCC tissues and non-tumor tissues by MSP. (A) Methylation of MUC2 promoter in HCC and corresponding non-carcinoma tissues. M, hypermethylation; PM, partial methylation; U, unmethylation; (B) Representative patterns of MUC2 promoter methylation. U, reaction specific for unmethylated DNA; M, reaction specific for methylated DNA. MI, The methylation index. -ΔCt, - (CTMUC2 - CTβ-actin).
Ling et al. BMC Medical Genetics 2013 14:14 doi:10.1186/1471-2350-14-14