The mean Young ManiaRating Scale (YMRS) scorebefore (0 weeks) andafter 4 and 8weeks of olanzapine treatmentin patients with bipolardisorder (BPD). The mean YMRS score was significantly lower after 4 weeks of treatment with olanzapine (mean YMRS score before medication: 30.31±10.81; after 4 weeks of medication: 10.53±9.82; Wilcoxon rank sum test: *p= 0.001). The mean YMRS score of the BPD patients was further significantly reduced after 8 weeks after medication compared with the score after 4 weeks of medication (YMRS score after 8 weeks of medication: 2.5±2.20; Wilcoxon rank sum test: #p= 0.005). The YMRS mean scores before and after treatment are indicated by horizontal lines.
Zain et al. BMC Medical Genetics 2012 13:91 doi:10.1186/1471-2350-13-91