Table 4

Summary of fine mapping of replicated loci
SNP (local SNP if replicated locally) Haplotype block length (CEU) Haplotype block length (YRI) Comment
rs10401969 96 kb 88 kb
rs11869286 19 kb 49 kb
rs12678919 53 kb Not in block Higher peak is rs12679834 (p = 0.0010), in same haplotype block as rs12678919 in CEU, not in YRI. (Figure 2)
rs2081687 17 kb 1 kb Rs10088541 is a higher peak nearby (p = 7.5 x 10-5). R2 between rs10088541 and index SNP = 0.75 among CEU, but only 0.03 in HUFS. (Figure 3)
rs2131925 298 kb 201 kb
rs2972146 (rs2943652) Index SNP not successfully genotyped or imputed in HUFS: no fine-mapping comparisons possible.
rs3764261 (rs173539) Index SNP not successfully genotyped or imputed in HUFS: no fine-mapping comparisons possible.
rs3764261 (rs1800775) Index SNP not successfully genotyped or imputed in HUFS: no fine-mapping comparisons possible.
rs3764261 (rs4783961) Index SNP not successfully genotyped or imputed in HUFS: no fine-mapping comparisons possible.
rs4420638 Not in block Not in block
rs629301 16 kb 468 bp (Figure 4)
rs7941030 (rs6589939) 40 kb Not in block Higher peak is at SNP rs6589939 (p = 0.005 vs. p = 0.10), which is in the same 40 kb block as the index SNP among CEU.

Adeyemo et al.

Adeyemo et al. BMC Medical Genetics 2012 13:88   doi:10.1186/1471-2350-13-88

Open Data