fl-SMN2 transcript levels among the individuals with different SMN2 copy numbers. Mean fl-SMN2 transcript levels in healthy individuals (normal controls and healthy carriers) with a single copy of SMN2 were 6.3895 ± 1.56, 11.48 ± 8.01 for those with two copies of SMN2, and 15.61 ± 11.39 for patients with three SMN2 copies. No correlation was observed between fl-SMN2 transcript level and SMN2 copy numbers (F = 0.391, P = 0.679).
Yu-jin et al. BMC Medical Genetics 2012 13:86 doi:10.1186/1471-2350-13-86