Genetic variants associated with breast size also influence breast cancer risk
23andMe, Inc., Mountain View, CA 94043, USA
BMC Medical Genetics 2012, 13:53 doi:10.1186/1471-2350-13-53Published: 30 June 2012
Additional file 1:
Quantile-quantile plot of association with breast size. Observed p-values versus theoretical p-values under the null hypothesis of no association. The genomic control inflation factor for the study was 1.047 and is indicated by the red line; approximate 95% confidence intervals are given by the blue curves.
Format: TIFF Size: 89KB Download file
Additional file 2:
All SNPs withp<10−4for breast size. Alleles are listed as major/minor. MAF is the frequency of the minor allele in Europeans, and and are the estimated imputation accuracies on the two genotyping platforms.
Format: XLS Size: 483KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 3:
Associations with breast size in three regions with suggestive SNPs. Colors depict the squared correlation (r2) of each SNP with the most associated SNP (which is shown in purple). Gray indicates SNPs for which r2 information was missing.
Format: PNG Size: 555KB Download file