The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children
1 Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Uppsala SE 75124, Sweden
2 Department of Nutrition & Dietetics, Harokopio University of Athens, Athens, Greece
3 Department for Clinical Science, Intervention and Technology (CLINTEC), department of Pediatrics, Karolinska Institute, Karolinska University Hospital, Huddinge, B57, 141 86, Stockholm, Sweden
4 First Department of Pediatrics, Athens University Medical School, Aghia Sophia Children’s Hospital, Thivon and Levadias, 115 27, Goudi, Athens, Greece
5 Pediatrics, National Childhood Obesity Centre, Stockholm, Sweden
BMC Medical Genetics 2012, 13:36 doi:10.1186/1471-2350-13-36Published: 17 May 2012
Additional file 1:
Figure S1. Linkage disequilibrium (LD) pattern of the proximal region of the obesity associated SNP rs2241423 (marked in red). R-squared scores are used to visualize the LD pattern. Linkage disequilibrium-analysis using confidence intervals according to Gabriel et al.  identifies rs2241423 to lie in a haplotype block of about 40 kb encompassing the last intron and exon of MAP2K5 as well as a 10 kb downstream region.
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Additional file 2:
Table S1. Association of rs2241423 to measurements of body adiposity in greek children. * - skewed quantitative variables were normalized by logarithmation.
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