Additional file 3.

Table S2. Genes consisting of the HDNs. Genes consisting of the HDNs of Figure 2 are listed in this Table. These genes were selected when being functionally similar to the drug targets of each state (SSM > 0.5), as well as when having PPI connections among themselves. Accordingly, the genes "common to both HDNs" are different between IBDmild and IBDsevere, because SSM scoring is different between the HDNs. Genes are boldfaced when they are susceptibility loci for IBD detected by GWAS [8,9]. Genes are underlined when they are selected as differential expressed genes by SAM statistics (FDR < 0.05) [39] with GSE6731. Abbreviations for gene names are lilsted in Additional file 5: Table S1.

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Suzuki et al. BMC Medical Genetics 2012 13:25   doi:10.1186/1471-2350-13-25