Table 1

Disease pairs with comparable genetic overlaps have highly variable values for MCS
Disease pair Genetic overlap MCS
Parkinson Disease & Gaucher Disease 2.57% 0.064803
Fragile X Syndrome & ADHD 2.57% 0.002577
Obesity & Deafness 2.57% 0.000476
α-1 Antitrypsin Deficiency & Lung Neoplasms 2.58% 0.000996
Rheumatic Fever & Rheumatic Heart Disease 12.90% 0.170213
Hypertension & Breast Neoplasms 12.91% 0.003824
Cystic Fibrosis & Sarcoma 13.01% 0.000000
Ovarian Neoplasms & Breast Neoplasms 29.47% 0.169344
Multiple Sclerosis & Rheumatoid Arthritis 29.45% 0.027160
Spinal Muscular Atrophy & Fragile X Syndrome 29.63% 0.000000
Diabetes Mellitus & Obesity 35.70% 0.183136
Autism & ADHD 37.00% 0.003636
Myotonic Dystrophy & Fragile X Syndrome 40.00% 0.000000
Asthma & Hypersensitivity 74.71% 0.392971
Cryptococcosis & Poliomyelitis 75.00% 0.000000

Duda et al.

Duda et al. BMC Medical Genetics 2012 13:114   doi:10.1186/1471-2350-13-114

Open Data