ROC curves using clinical attributes plus 160 SNPs as predictors. The red curve is obtained for the training of the Stage 1 samples, the blue curve is for the testing of the Stage 2 samples, the grey diagonal line is a theoretical curve representing random guess. Both the red and the blue curves are higher than the grey line, indicating better than random prediction; and they are similar to each other, suggesting the true predictability of the RF model. The p-value for the independent testing AUC to be different from 0.5 is 0.000266.
Xu et al. BMC Medical Genetics 2011 12:90 doi:10.1186/1471-2350-12-90