Table 1

Participant demographics and genotype distributions

Controls (n = 646)

FD, total (n = 53)

P2

EPS (n = 39)4

P2

PDS (n = 42)4

P2


Age (years)1

45 (19-78)

52 (21-82)

0.002

50 (21-82)

0.021

51 (21-82)

0.015

Sex (male%)

50.5

49.1

0.887

41.0

0.323

52.4

0.874

Smoking (%)

32.7

28.3

0.647

23.1

0.289

31.0

1.000

Drinking (%)

29.6

32.1

0.755

30.8

0.858

33.3

0.604

5-HTTLPR genotype (%)

SS

69.3

56.6

61.5

50.0

SL

26.9

37.7

30.8

42.9

LL

3.7

5.7

0.117

7.7

0.257

7.1

0.019

P for HWE3

0.173

0.889

0.405

0.746


1Data are shown as median (range).

2P vs. controls by Mann-Whitney U-test (for age) or Fisher's exact test (for other variables).

3P for deviation from Hardy-Weinberg equilibrium (HWE).

4Twenty eight subjects are simultaneously classified EPS and PDS phenotype.

FD, functional dyspepsia; EPS, epigastric pain syndrome; PDS, postprandial distress syndrome

Toyoshima et al. BMC Medical Genetics 2011 12:88   doi:10.1186/1471-2350-12-88

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