Open Access Research article

Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma

Melanie Rushefski23, Richard Aplenc23, Nuala Meyer1, Mingyao Li2, Rui Feng2, Paul N Lanken1, Robert Gallop2, Scarlett Bellamy2, A Russell Localio2, Sheldon I Feinstein4, Aron B Fisher4, Steven M Albelda1 and Jason D Christie12*

Author Affiliations

1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, 19104, USA

2 Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, 19104, USA

3 Division of Oncology, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, 19104, USA

4 Institute for Environmental Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, 19104, USA

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BMC Medical Genetics 2011, 12:77  doi:10.1186/1471-2350-12-77

Published: 31 May 2011

Additional files

Additional file 1:

PCR primers and cycling conditions.

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Additional file 2:

Detectable relative risk vs. disease allele frequency.

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Additional file 3:

Sequencing variants separated by race and case-control status.

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Additional file 4:

Confidence score for sequencing genotypes with only one variant.

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Additional file 5:

Hardy-Weinberg equilibrium values.

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Additional file 6:

Dominant and recessive models in African Americans and European Americans.

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