Fetal results. QQ-plots showing the most significant fetal genes for the different designs. A) Single locus, case-parent triad. B) Haplotype, case-parent triad. C) Single locus, hybrid. D) Haplotype, hybrid. The observed p-values for each gene are plotted against the expected p-values. If there is no effect of the genes, the p-values will be positioned on the straight line. The grey area along the straight line shows the point-wise confidence interval for the expected p-values. Correction for multiple testing was performed within each gene. There have been done no adjustments for covariates in the hybrid analysis.
Myking et al. BMC Medical Genetics 2011 12:174 doi:10.1186/1471-2350-12-174