Table 5

Sequence changes detected by CD22 exon sequencing

Chr. Pos. (Build 37)

Gene Feature

Allele Change

SNP Identifier

MAF (Caucasian)

mRNA Position

Amino Acid

Residue Change


1

35,823,999

Intron 3

C- > T

rs881456

0.021 (0.000)

2

35,824,019

Intron 3

C- > G

rs10419538

0.104 (0.181)

3

35,829,381

Intron 6

A- > G

rs7248108

0.042 (0.042)

4

35,831,986

Exon 7

C- > T

rs25677

0.042 (0.000)

1529

484

C- > C

5

35,832,381

Exon 8

G- > A

0.021

1721

548

R- > K

6

35,832,886

Intron 9

T- > A

0.021

7

35,835,940

Intron 10

C- > T

rs45453699

0.313

8

35,836,512

Exon 12

A- > G

0.021

2293

739

R- > G

9

35,836,530

Exon 12

G- > A

rs10406069

0.104 (0.292)

2311

745

G- > D

10

35,836,600

Exon 12

C- > A

rs34826052

0.042

2381

768

P- > P

11

35,837,148

Intron 13

G- > A

hCV25603572

0.021 (0.05)

12

35,837,150

Intron 13

C- > T

0.021

13

35,837,327

Intron 13

C- > T

rs58156121

0.063

14

35,837,428

Intron 13

G- > A

rs12985354

0.208 (0.383)

15

35,837,694

3'-UTR

C- > T

rs73031792

0.250

2715

16

35,837,705

3'-UTR

A- > G

rs35529786

0.167

2726

17

35,837,724-5

3'-UTR

GC I/D1

rs34472317

0.042

2745-6

18

35,837,813

3'-UTR

C- > T

0.042

2834

19

35,837,846

3'-UTR

C- > T

rs16970255

0.042 (0.000)

2867

20

35,838,076

3'-UTR

C- > T

rs3088063

0.042 (0.055)

3097


1Variant allele is GC insertion.

For definitions, see footnote to Table 4.

For details, see Additional file 11, Table S9 and Additional file 12, Table S10.

Lillvis et al. BMC Medical Genetics 2011 12:14   doi:10.1186/1471-2350-12-14

Open Data