Table 3

Number of patients who had HLA-B*5801 allele positive and summary odds ratios

Author

Year

HLA-B*5801

Positive/Total

Odds Ratio (OR)

95% Confidence Interval


SJS/TEN Cases

(n)

Controls

(n)


Matched-control

Hung SI [10]

2005

21/21

20/135

242.27

14.11-4158.76

Tassaneeyakul W [13]

2009

27/27

7/54

348.33

19.15-6336.86

Kang HR [14]

2011

4/5

6/57

34.00

3.25-356.12

Jung JW [15]

2011

2/2

41/432

47.17

2.23-999.15

Pooled OR

96.60

24.49-381.00

Population-control

Hung SI [10]

2005

21/21

19/93

164.28

9.52-2833.92

Kaniwa N [11]

2008

4/10

6/493

54.11

12.08-242.41

Lonjou C [12]

2008

19/31

28/1822

101.45

44.98-228.82

Kang HR [14]

2011

4/5

59/485

28.88

3.17-262.79

Jung JW [15]

2011

2/2

59/485

35.84

1.70-755.61

Pooled OR

79.28

41.53-151.35


Abbreviations: SJS = Stevens-Johnson Syndrome, TEN = Toxic Epidermal Necrolysis; OR = Odds Ratio

Somkrua et al. BMC Medical Genetics 2011 12:118   doi:10.1186/1471-2350-12-118

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