Table 2

Patients' demographic information

Author

Year

% Male

Mean age,

yr (range)

Ethnicity

Country

Allopurinol Dose, mg/day (range)

Actual Duration of Allopurinol Exposure



SJS/TEN Cases

Controls

SJS/TEN Cases

Controls

Cases

Control

Cases

Control


Hung SI [10]

2005

52.4

92.6a

62.4 (25-91)

56.0 (21-84)b

Han Chinese

Taiwan

100

(50-300)

150

(100-400)

26 d

(~1-56 d)

22 m

(6-107 m)

Kaniwa N [11]

2008

80.0

NA

70.9 (53-83)

NA

Japanese

Japan

NR

NR

NR

NR

Lonjou C [12]

2008

58.1

NA

55.0 (21-83)

NA

Mixed European Populationc

NR

NR

NR

NR

NR

Tassaneeyakul W [13]

2009

55.6

79.63

65.0 (38-81)

63.5 (46-90)

Thai

Thailand

NR

NR

14 d

(3-50 d)

26 m

(3-600 m)

Kang HR [14]

2011

60.0

64.9d

50.0 (42-80)

51.0 (20-76)d

Korean

Korea

200

(100-300)

100

(50-200)

0.7 m

(0.2-1.1 m)

29.1 m

(6-72 m)

Jung JW [15]

2011

43.8

73.6d

41.4 (27-56)

35.9 (18-54)d

Korean

Korea

112.5

(74-151)

100

(50-150)

59 d

(14-105 d)

887 d

(66-1708 d)


Abbreviations: SJS = Stevens-Johnson Syndrome, TEN = Toxic Epidermal Necrolysis; NR = No Report; NA = Not Applicable; d = day(s); m = month(s)

a The percent male of matched-controls (% male in population controls is 55.91).

b Mean age in matched-controls (mean age in population controls is 53.9 (22-91)).

c Including Asian, South American, African, and European.

d The values from matched-controls group.

Somkrua et al. BMC Medical Genetics 2011 12:118   doi:10.1186/1471-2350-12-118

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