Table 1

Association of rs2891168 with coronary artery disease (CAD) and rs10811661 with type 2 diabetes (T2D) in different populations.

SNP

Risk allele

Risk allele frequency

Study population (no. cases)

OR§

(95% CI)

P-value

Genetic approach

Ref.*


rs2891168

G

0.59

Europeans (4251)

1.29

(1.20-1.38)

6 × 10-13

Case-control study

[15]

rs10811661

T

0.85

Finns (2314)

1.20

(1.07-1.36)

2.2 × 10-3

GWAS

[11]

0.82

UK (5681)

1.19

(1.11-1.28)

4.9 × 10-7

Meta-analysis of GWAS

[12]

0.83

Scandinavians Poles, US (6529)

1.20

(1.12-1.28)

5.4 × 10-8

GWAS

[13]

0.86

Dutch (9132)

1.30

(1.16-1.47)

1 × 10-5

Validation of GWAS

[24]

0.56

Chinese Hans (1302)

1.31

(1.12-1.54)

1 × 10-3

Replication study

[25]


* Ref: reference

§ OR: Odds Ratio

Gori et al. BMC Medical Genetics 2010 11:60   doi:10.1186/1471-2350-11-60

Open Data