Table 3

Distribution of TYMS homozygote status for MTHFR homozygotes

TYMS






Cohort 1

Cohort 2

Cohort 3

Cohort 4

Cohort 5

MTHFR

2_2

Other

2_2

Other

2_2

Other

2_2

Other

2_2

Other







CC

131

355

50

156

53

126

39

127

41

144

TT

27

101

9

32

10

42

4

26

13

63







P*

0.11

0.46

0.09

0.16

0.23

Consensus P0.02 (all cohorts), 0.04 (cohorts 3, 4 and 5 only)


* One-sided Fisher's exact test

Obtained using Stouffer's consensus combined P-value test [24]

Jennings et al. BMC Medical Genetics 2010 11:18   doi:10.1186/1471-2350-11-18

Open Data