Table 5

Recessive model study-specific and meta-analysis results

GenePD-PROGENI

Mayo-Perlegen LEAPS

GWAS Meta-analysis

Milan, Italian

Three Sample Meta-analysis


SNP

effect

p-value

effect

p-value

Direction of Effect

effect

p-value

effect

p-value

Direction of Effect

effect

p-value


rs10767971

4.23

9.3 × 10-6

2.35

1.3 × 10-1

++

3.71

4.3 × 10-6

2.40

2.6 × 10-2

+++

3.24

5.4 × 10-7


rs7577851

-8.64

1.2 × 10-4

-8.03

3.1 × 10-2

--

-8.48

9.8 × 10-6

-3.89

1.3 × 10-1

---

-6.85

8.7 × 10-6


rs1355637

-5.10

2.3 × 10-3

-14.25

4.1 × 10-5

--

-6.83

5.1 × 10-6

1.10

6.0 × 10-1

--+

-4.19

6.2 × 10-4


rs11899121

-3.41

8.0 × 10-5

-3.33

1.6 × 10-2

--

-3.39

3.5 × 10-6

0.43

6.5 × 10-1

--+

-1.99

6.3 × 10-4


rs12829697

-10.51

8.5 × 10-5

-10.33

3.0 × 10-2

--

-10.47

7.0 × 10-6

0.68

8.1 × 10-1

--+

-6.15

7.2 × 10-4


rs17663983

-16.72

1.2 × 10-5

-25.53

4.6 × 10-1

--

-16.83

8.1 × 10-6

5.77

2.9 × 10-1

--+

-9.46

2.3 × 10-3


rs12261736

-8.48

1.9 × 10-6

-0.56

8.9 × 10-1

--

-7.14

9.6 × 10-6

-0.73

4.9 × 10-1

---

-2.65

2.7 × 10-3


rs1420143

3.31

7.9 × 10-4

6.05

1.3 × 10-3

++

3.90

7.3 × 10-6

-0.52

5.9 × 10-1

++-

1.89

3.3 × 10-3


rs676495

-6.90

1.9 × 10-5

-11.27

2.4 × 10-1

--

-7.02

9.1 × 10-6

1.86

2.7 × 10-1

--+

-2.84

1.4 × 10-2


rs7556447

-13.34

2.1 × 10-5

-11.11

1.9 × 10-1

--

-13.08

7.9 × 10-6

-0.44

7.7 × 10-1

---

-3.01

2.3 × 10-2


rs4791571

-5.18

1.3 × 10-5

-6.39

2.4 × 10-1

--

-5.23

5.9 × 10-6

2.57

3.5 × 10-2

--+

-1.52

6.9 × 10-2


Latourelle et al. BMC Medical Genetics 2009 10:98   doi:10.1186/1471-2350-10-98

Open Data