BMC Medical Genetics

official impact factor 2.44

Open Access Research article

Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project

Marie-Lise Grisoni1,2, Carole Proust1,2, Mervi Alanne3, Maylis DeSuremain1,2, Veikko Salomaa4, Kari Kuulasmaa4, François Cambien1,2, Viviane Nicaud1,2, Per-Gunnar Wiklund5, Jarmo Virtamo4, Frank Kee6, Laurence Tiret1,2, Alun Evans6 and David-Alexandre Tregouet1,2*

Author Affiliations

1 INSERM, UMR_S 937, F-75013, Paris, France

2 UPMC Univ Paris 06, UMR_S 937, F-75013, Paris, France

3 Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland

4 Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland

5 Department of Internal Medicine, University of Umeå, Umeå, Sweden

6 Centre Department of Epidemiology and Public Health, Queen's University of Belfast, Belfast, UK

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BMC Medical Genetics 2009, 10:44 doi:10.1186/1471-2350-10-44

Published: 27 May 2009

Additional files

Additional file 1:

Allele frequencies of the IL18R1 and IL18RAP SNPs in the MORGAM subcohorts.

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Additional file 2:

Haplotype frequencies and odds ratios of IL18R1 and IL18RAP genes. Table 1: Haplotype frequencies of the IL18R1 gene in the MORGAM cohorts (cases and non-cases). Table 2: Odds Ratio for CVD risk associated with IL18R1 gene haplotypes in the MORGAM cohorts. Table 3: Haplotype frequencies of the IL18RAP gene in the MORGAM cohorts (cases and non-cases). Table 4: Odds Ratio for CVD risk associated with IL18RAP gene haplotypes in the MORGAM cohorts.

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Open Data