Table 2

The 25 included studies

Study

Total number Of patients

Suspected Condition

True +ve

False +ve

False -ve

True -ve

N

Sensitivity (95% CI)

Specificity (95% CI)

Likelihood ratio-positive (95% CI)

Likelihood ratio-negative (95% CI)*


Adamek[9]

86

Abnormality

42

1

5

12

60

0.89 (0.77, 0.95)

0.92 (0.67, 0.99)

11.62 (1.76, 76.57)

0.12 (0.02, 0.76)

Adamek

81

Malignancy

22

0

5

33

60

0.81 (0.63, 0.92)

1.00 (0.90, 1.00)

54.64 (3.47, 861.18)

0.20 (0.01, 3.14)

Angulo[11]

73

Normal

19

2

3

46

70

0.86 (0.67, 0.95)

0.96 (0.86, 0.99)

20.73 (5.28, 81.31)

0.14 (0.04, 0.56)

Angulo

70

dilitation CBD

38

2

3

27

70

0.93 (0.81, 0.97)

0.93 (0.78, 0.98)

13.44 (3.52, 51.33)

0.08 (0.02, 0.30)

Angulo

72

Obstruction

37

3

0

39

79

1.00 (0.91, 1.00)

0.91 (0.76, 0.97)

11.00 (3.74, 32.36)

0.00

Angulo

70

Choledocholithiasis

5

1

5

59

70

0.50 (0.24, 0.76)

0.98 (0.91, 1.00)

30.00 (3.90, 230.73)

0.51 (0.07, 3.91)

Angulo

70

PSC

19

1

4

46

70

0.83 (0.63, 0.93)

0.98 (0.89, 1.00)

38.83 (5.53, 272.37)

0.18 (0.03, 1.25)

Barish[12]

29

Dilitation

13

0

2

6

21

0.87 (0.62, 0.96)

1.00 (0.61, 1.00)

11.81 (0.81, 172.17)

0.17 (0.01, 2.45)

Calvo[13]

61

Choledocholithiasis

29

2

3

10

44

0.91 (0.76, 0.97)

0.83 (0.55, 0.95)

5.44 (1.53, 19.36)

0.11 (0.03, 0.40)

Chan[14]

47

Choledocholithiasis

18

4

1

22

45

0.95 (0.75, 0.99)

0.85 (0.66, 0.94)

6.16 (2.48, 15.26)

0.06 (0.03, 0.15)

Demartines[15]

40

Choledocholithiasis

19

2

0

19

40

1.00 (0.83, 1.00)

0.90 (0.71, 0.97)

10.50 (2.81, 39.24)

0.00

Dwerryhouse[16]

40

Choledocholithiasis

7

2

1

28

38

0.88 (0.53, 0.98)

0.93 (0.79, 0.98)

13.13 (3.35, 51.36)

0.1 (0.03, 0.52)

Guibaud[18]

79

Obstruction

72

0

7

47

126

0.91 (0.83, 0.96)

1.00 (0.92, 1.00)

87.00 (5.52, 1372.23)

0.09 (0.01, 1.49)

Guibaud

Choledocholithiasis

26

2

6

92

126

0.81 (0.65, 0.91)

0.98 (0.93, 0.99)

38.19 (9.60, 151.97)

0.19 (0.05, 0.76)

Guibaud

Malignancy

12

2

2

110

126

0.86 (0.60, 0.96)

0.98 (0.94, 1.00)

48.00 (11.96, 192.72)

0.15 (0.04, 0.58)

Holzknecht[20]

61

Choledocholithiasis

12

3

2

46

63

0.86 (0.60, 0.96)

0.94 (0.83, 0.98)

14.00 (4.58, 42.78)

0.15 (0.05, 0.47)

Holzknecht

Dilatation

32

2

2

26

62

0.94 (0.81, 0.98)

0.93 (0.77, 0.98)

13.18 (3.46, 50.23)

0.06 (0.02, 0.24)

Holzknecht

Stenosis

31

3

5

22

61

0.86 (0.71, 0.94)

0.88 (0.70, 0.96)

7.18 (2.46, 20.91)

0.16 (0.05, 0.46)

Holzknecht

Overall

43

3

4

12

62

0.91 (0.80, 0.97)

0.80 (0.55, 0.93)

4.57 (1.66, 12.63)

0.11 (0.04, 0.29)

Laokpessi[21]

101

Choledocholithiasis

105

0

8

34

147

0.93 (0.87, 0.96)

1.00 (0.90, 1.00)

64.78 (4.13, 1015.86)

0.08 (0.00, 1.19)

Lee[22]

46

Malignancy

17

2

4

23

46

0.81 (0.60, 0.92)

0.92 (0.75, 0.98)

10.12 (2.64, 38.86)

0.21 (0.05, 0.79)

Lomanto[23]

136

Choledocholithiasis

22

0

2

38

62

0.92 (0.74, 0.98)

1.00 (0.91, 1.00)

70.20 (4.46, 1105.97)

0.10 (0.01, 1.60)

Lomas[24]

76

Choledocholithiasis

9

2

0

58

69

1.00 (0.70, 1.00)

0.97 (0.89, 0.99)

30.00 (7.68, 117.19)

0.00

Lomas

Stricture

19

1

0

49

69

1.00 (0.83, 1.00)

0.98 (0.90, 1.00)

50.00 (7.18, 348.04)

0.00

Macaulay[25]

29

Dilatation

18

1

0

10

29

1.00 (0.82, 1.00)

0.91 (0.62, 0.98)

11.00 (1.70, 71.28)

0.00

Regan[26]

23

Choledocholithiasis

14

1

1

7

23

0.93 (0.70, 0.99)

0.88 (0.53, 0.98)

7.47 (1.19, 46.94)

0.08 (0.01, 0.48)

Reinhold[27]

110

Obstruction

69

0

7

34

110

0.91 (0.82, 0.95)

1.00 (0.90, 1.00)

63.18 (4.03, 991.27)

0.10 (0.01, 1.55)

Reinhold

Choledocholithiasis

27

3

3

77

110

0.90 (0.74, 0.97)

0.96 (0.90, 0.99)

24.00 (7.86, 73.31)

0.10 (0.03, 0.32)

Soto 1996[28]

46

Dilatation

26

1

1

16

44

0.96 (0.82, 0.99)

0.94 (0.73, 0.99)

16.37 (2.44, 109.77)

0.04 (0.01, 0.26)

Soto 2000[29]

57

Choledocholithiasis

23

1

1

24

49

0.96 (0.80, 0.99)

0.96 (0.80, 0.99)

23.96 (3.50, 163.78)

0.04 (0.01, 0.30)

Soto 2000[30]

51

Choledocholithiasis

25

0

1

25

51

0.96 (0.81, 0.99)

1.00 (0.87, 1.00)

49.11 (3.15, 765.62)

0.06 (0.00, 0.88)

Stiris[31]

50

Choledocholithiasis

28

1

4

17

50

0.88 (0.72, 0.95)

0.94 (0.74, 0.99)

15.75 (2.33, 106.28)

0.13 (0.02, 0.89)

Sugiyama[32]

159

anamalous PBJ

9

0

2

148

159

0.82 (0.52, 0.95)

1.00 (0.97, 1.00)

235.92 (14.60, 3811.82)

0.21 (0.01, 3.38)

Taylor[33]

146

Choledocholithiasis

45

9

1

74

129

0.98 (0.89, 1.00)

0.89 (0.81, 0.94)

9.02 (4.86, 16.74)

0.02 (0.01, 0.05)

Taylor

Stricture

12

1

0

118

131

1.00 (0.76, 1.00)

0.99 (0.95, 1.00)

118.00 (16.76, 830.78)

0.00

Textor[34]

150

PSC

29

1

4

108

142

0.88 (0.73, 0.95)

0.99 (0.95, 1.00)

95.79 (13.56, 676.70)

0.12 (0.02, 0.86)

Varghese[35]

191

Choledocholithiasis

31

3

3

154

191

0.91 (0.77, 0.97)

0.98 (0.95, 0.99)

47.72 (15.48, 147.06)

0.09 (0.03, 0.28)

Zidi[36]

70

Choledocholithiasis

28

0

21

21

70

0.57 (0.43, 0.70)

1.00 (0.85, 1.00)

25.08 (1.60, 392.61)

0.44 (0.03, 6.89)


* With likelihood ratios of zero, the data are unsuitable for the calculation of 95% confidence intervals.

Kaltenthaler et al. BMC Medical Imaging 2006 6:9   doi:10.1186/1471-2342-6-9

Open Data