Table 1 |
|
| Criteria of high, moderate and low study quality, mainly according to QUADAS21 | |
| High: small risk of bias | Prospective study design. Particular emphasis on the following: |
| ● adequately described patients constituting a representative and clinically relevant sample (QUADAS items 1, 2). | |
| ● the index test should not form part of the reference standard (item 7). | |
| ● evaluators should be masked to results of index test and reference test (items 10, 11) | |
| ● the tests should be described in sufficient detail to permit replication (items 8, 9). | |
| ● sample size ≥ 5000. | |
| ● diagnostic accuracy presented as sensitivity and specificity. | |
| Moderate: moderate risk of bias | Prospective study design |
| Since no prospective studies based on digital mammography could be identified, scanned analogue images were accepted. Otherwise the same criteria as for high quality were required. | |
| Low: high risk of selection and/or verification bias | Retrospective study design. Selected or enriched samples |
Azavedo et al. BMC Medical Imaging 2012 12:22 doi:10.1186/1471-2342-12-22
