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Table 1
Difference of ROI volumes between the automated and the manual protocol
Program	Perfscape/Neuroscape	PMA	PMA with filtering *	Stroketool	Stroketool with filtering *
	Median	Median	Median	Median	Median
	IQR	IQR	IQR	IQR	IQR
Parameter
Tmax 4 s	25.80	123.68	64.91	122.89	37.50
Tmax 4 s	12.8–66.1	75.2–206.8	27.3–138.1	75.6–176.5	14.9–75.3
Tmax 6 s	12.74	29.48	4.83	53.18	7.75
Tmax 6 s	4.1–34.4	16.4–67.8	1.0–22.4	34.0–82.6	1.8–18.3
Tmax 8 s	8.05	23.16	2.68	31.78	1.67
Tmax 8 s	2.6 - 28.1	13.5 – 55.4	0.4 – 15.8	16.1 – 50.1	0.2 – 6.5
MTT 5 s	186.78	35.12	11.59	129.35	58.74
MTT 5 s	151.4–248.5	17.8–87.8	3.4–44.1	82.5–225.7	21.8–130.5
MTT 6 s	154.40 114.8–207.0	16.76 8.4–49.0	4.34 0.9–18.4	80.18 49.1–143.6	26.51 8.0–63.7
MTT 8 s	94.24	7.36	0.77	33.82	6.07
MTT 8 s	55.0–143.3	3.8–17.4	0.3–3.9	20.9–57.6	1.6–18.8
CBF highest threshold	209.92	54.35	23.05	134.50	67.28
CBF highest threshold	160.0–262.8	27.5–107.9	7.6–64.4	89.9–193.0	39.0–110.2
CBF medium threshold	151.93	36.14	10.51	87.28	35.27
CBF medium threshold	97.6–212.2	18.6–65.9	3.7–36.5	59.4–134.0	18.1–61.7
CBF lowest threshold	63.66	23.40	4.33	53.95	12.73
	39.6–119.4	13.3–39.3	1.4–15.3	37.2–83.0	6.6–28.4

CBF indicates cerebral blood flow; MTT mean transit time; IQR interquartile range. All values are in ml. * Values indicate volumes after additional CSF filtering in SPM8.

Galinovic et al. BMC Medical Imaging 2012 12:16 doi:10.1186/1471-2342-12-16

Table 1