Table 2

The number and type of the risk factors that were present in the children with HFMD seen in the 2000/3 and 2006 outbreaks

Risk factors that were present

First phase of study (2000/3)

Second phase of study (2006)



HFMD-CNS (N = 102)

HFMD-Non-CNS (N = 83)

Mild HFMD

(N = 540)

HFMD-CNS

(N = 250)

HFMD-Non-CNS (N = 186)

Mild HFMD

(N = 294)



No. of patients with none of the 3 risk factor

2

9

352

11

52

208





Peak temperature ≥ 38.5°C only

1

8

7

29

32

34

History of lethargy only

5

15

27

16

11

17

Total duration of fever ≥ 3 only

9

15

122

32

35

30



No. of patients with 1 risk factor

15

38

156

77

78

81



Peak temperature ≥ 38.5°C plus history of lethargy

2

3

1

11

7

2

Peak temperature ≥ 38.5°C plus total duration of fever ≥ 3 days

25

15

8

76

31

3

Total duration of fever ≥ 3 days plus history of lethargy

26

12

19

21

5

0



No. of patients with 2 risk factors

53

30

28

108

43

5



No. of patients with 3 risk factors (Peak temperature ≥ 38.5°C plus total duration of fever ≥ 3 days plus history of lethargy)

32

6

4

54

13

0


Note:

HFMD: Hand, foot, and mouth disease

HFMD-CNS: Hand, foot, and mouth disease with central nervous system complication

HFMD-Non-CNS: Severe HFMD without central nervous system involvement

Ooi et al. BMC Infectious Diseases 2009 9:3   doi:10.1186/1471-2334-9-3

Open Data