Effectiveness of quarantine with and without use of rapid diagnostic testing as a function of time since infection (i.e., time since arrival). Different effectiveness measures of quarantine are comparatively shown. The dashed line represents the effectiveness of quarantine, measured as the relative reduction of the risk of releasing "symptomatic infected" individuals (regardless of infectiousness) based on the incubation period alone. The two continuous lines measure the effectiveness as the relative reduction of the risk of releasing "infectious individuals" into the community, based on the incubation period, generation time and probability of symptomatic disease, with (thin) and without (thick) use of rapid diagnostic testing. The sensitivity of the rapid diagnostic test was assumed to be 69.0% (based on current test performance for seasonal influenza A ).
Nishiura et al. BMC Infectious Diseases 2009 9:27 doi:10.1186/1471-2334-9-27