Table 1

Characterization (antibiogram, PCR-RFLP of the coagulase gene and PFGE) of low and high-level mupirocin resistant S. aureus isolated in Nigeria and South Africa

Strain No

Antibacterial

resistance patterns

MUP MIC

(mg/L)

mupA

gene

Coagulase gene

(± 20 bp)

PCR-RFLP Coagulase

gene (bp)

PFGE

type


A1

PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Hg

12

-

800

324, 405

A


A2

PEN, OX, GN, TET, TS, RF, MU (L)

24

-

650

81, 567

B


A3

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

16

-

850

324, 405

A


A4

PEN, OX, GN, TET, TS, RF, MU (L), Cad, Hg

24

-

650

81, 567

B


A5

PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

12

-

800

324, 405

A1


A6

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

8

-

800

81, 324, 405

A


A7

PEN, OX, GN, ERY, TET, TS, RF, MU (L), Cad

24

-

650

81, 567

B1


A8

PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

8

-

800

81, 324, 405

A


A9

PEN, OX, GN, ERY, TET, TS, RF, MU (L), Cad, Hg

24

-

650

81, 567

B2


A10

PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Hg

12

-

800

81, 324, 405

A


A11

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

8

-

800

81, 324, 405

A


A12

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Hg

12

-

850

81, 324, 405

A2


A13

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Hg

8

-

800

81, 324, 405

A1


A14

PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb

12

-

800

81, 324, 405

A


A15

PEN, OX, GN, ERY, TET, TS, RF, MU (H), Cad

>1024

+

650

81, 567

B3


P1929

TM, TET, MU (H), Cad

>1024

+

750

243, 486

C


35 IBA

TET, MU (H), Cad

>1024

+

800

81, 162, 567

D


    KEY.
PEN – Penicillin, OX – Oxacillin, GN – Gentamicin, ERY – Erythromycin, CHL – Chloramphenicol,

TET – Tetracycline, TS – Trimethoprim, RF – Rifamipicin, CIP – Ciprofloxacin,

MU (H) – High-level mupirocin resistance, MU (L) – Low-level mupirocin resistance

Heavy metals – Cad: Cadmium acetate; Hg: Mercuric chloride Nucleic acid binding compounds – Eb: Ethidium bromide; Pi: Propamidine isethionate

Shittu et al. BMC Infectious Diseases 2009 9:10   doi:10.1186/1471-2334-9-10

Open Data