|
False positive cases. |
||||
| Pt. |
Aspergillus DNA (fg/pellet) |
BAL Culture |
Clinical Diagnosis |
Computed tomography scan results and other clinical information |
|
|
||||
| 1 |
5230 |
negative |
DAH |
Organizing pneumonia on lung biopsy with pulmonary hemorrhage; treated with ambisome empirically; No IPA at autopsy |
| 2 |
230 |
negative |
BOOP |
Bilateral patchy opacities; no mould active antifungal therapy given |
| 3 |
60 |
negative |
Unknown |
Nodular right middle lobe infiltrate treated with levofloxacin; exposure to hay |
| 4 |
340 |
negative |
IPA |
Multiple bilateral nodules; treated as IPA with voriconazole + caspofungin |
| 5 |
320 |
negative |
DAH |
Bilateral geographic grounds glass opacities; treated with caspofungin |
| 6 |
80 |
negative |
BOOP |
Numerous bilateral ground glass opacities; treated with prednisone but no antifungal therapy |
| 7 |
170 |
negative |
Influenza pneumonia/PCP |
Left lung infiltrates; no antifungal therapy except for Pneumocystis |
|
Additional information about false positive (FP) cases as identified by qPCR. Pt.: patient; BOOP: Bronchiolitis obliterans with organizing pneumonia; DAH: Diffuse alveolar hemorrhage; PCP: Pneumocystis pneumonia. | ||||
Khot et al. BMC Infectious Diseases 2008 8:73 doi:10.1186/1471-2334-8-73 |
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