|
Basic characteristics of healthcare-associated infections (HAIs) and of nosocomial fevers of unknown origin (nFUO) |
|||
| Item |
HAI (N = 263) |
nFUO (N = 464) |
P-value |
|
|
|||
| Number of patients included (in total, n = 411) |
181 |
230 |
- |
| Age at diagnosis of HAI/nFUO |
< 0.001 |
||
| < 5 years |
84 (32%) |
174 (38%) |
|
| 5 years to < 10 years |
58 (22%) |
130 (28%) |
|
| 10 years to < 15 years |
56 (21%) |
99 (21%) |
|
| ≥ 15 years |
65 (25%) |
61 (13%) |
|
| Underlying disease |
0.07 |
||
| Acute lymphoblastic leukemia |
86 (33%) |
136 (29%) |
|
| Acute myeloid leukemia |
34 (13%) |
40 (9%) |
|
| Lymphoma |
29 (11%) |
48 (10%) |
|
| solid tumor outside central nervous system |
70 (27%) |
166 (36%) |
|
| solid tumor of central nervous system |
34 (13%) |
65 (14%) |
|
| non-malignant hematologic disease |
10 (4%) |
9 (2%) |
|
| Relapse of malignancy |
54 (21%) |
68 (15%) |
0.049 |
| Therapy§ preceding HAI/nFUO |
0.18 |
||
| conventional chemotherapy |
214 (81%) |
391 (84%) |
|
| high-dose chemotherapy & autologous SCT |
22 (8%) |
44 (9%) |
|
| high-dose chemotherapy & allogeneic SCT |
26 (10%) |
25 (5%) |
|
| radiation therapy |
14 (5%) |
22 (5%) |
|
| Neutropenia at diagnosis of HAI/nFUO |
145 (55%) |
232 (50%) |
0.19 |
|
Indicated are numbers (proportion of respective events). §Since more than one treatment modality was applicable, the numbers do not add up to 263 and 464, respectively. | |||
Simon et al. BMC Infectious Diseases 2008 8:70 doi:10.1186/1471-2334-8-70 |
|||