Table 2

Pathogenic NP organisms and TMP-SMX status at baseline

Total

Not on TMP-SMX at baseline

On TMP-SMX at baseline

Previously received TMP-SMX


†Pathogenic organisms

S. pneumoniae

48 (26.5%)

9 (5%)

36 (19.9%)

3 (1.7%)

§Gram negative respiratory organism (M. catarrhalis, H. influenzae)

48 (26.5%)

7 (3.2%)

35 (19.3%)

6 (3.3)

S. aureus

44 (24.3%)

10 (5.5%)

31 (17.1%)

3 (1.7%)

Enterobacteriacae

32 (17.7%)

13 (9.9%)

18 (9.9%)

1 (0.5%)

Non-fermenters including Pseudomonas aeruginosa #

5 (2.8%)

4 (2.2%)

1 (0.5%)

0

Acinetobacter species ¶

4 (2.2%)

3 (1.7%)

1 (0.5%)

0


10 subjects had 2 organisms and 2 had 3 organisms isolated from a NP swab.

§M. catarrhalis n – 22; H. influenzae – n – 26

TMP-SMX exposure: More than 1 organism per subject

Organisms not included – Coagulase negative staphylococcus – 10; Streptococcus viridans – 2; other commensals – 11; no growth – 10; contaminants – 3

# p = 0.0104 (Fisher's Exact 2-tail test)

¶p = 0.048 (Fisher's Exact 2-tail test)

Cotton et al. BMC Infectious Diseases 2008 8:40   doi:10.1186/1471-2334-8-40

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