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Risk factors for CS-MRSA^ infection in HIV infected patients. Multivariate analysis. |
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| Cases n = 27 |
Controls n = 54 |
Univariate analysis |
Multivariate analysis |
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|
|
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| Odds Ratio§ |
95% CI^^ |
p* |
Odds Ratio§ |
95% CI^^ |
p* |
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|
|
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| HIV risk factor, n (%) |
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| IDU (intravenous drug user) |
15 |
31 |
1.00 |
- |
- |
- |
- |
- |
- |
- |
| Homosexual |
2 |
7 |
0.50 |
0.08 |
3.02 |
0.449 |
- |
- |
- |
- |
| Heterosexual |
5 |
7 |
1.70 |
0.41 |
6.97 |
0.463 |
- |
- |
- |
- |
| Unknown |
5 |
9 |
1.18 |
0.33 |
4.22 |
0.801 |
- |
- |
- |
- |
| Cumulative hospital stay (days) in the previous year |
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| (per an increase of 5 days) |
- |
- |
1.11 |
1.02 |
1.22 |
0.020 |
1.14 |
1.01 |
1.29 |
0.041 |
| Outpatient visits in the previous year |
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| 0–1 |
17 |
19 |
1.00 |
- |
- |
- |
1.00 |
- |
- |
- |
| more than 1 |
10 |
35 |
0.34 |
0.13 |
0.92 |
0.034 |
0.26 |
0.07 |
1.01 |
0.051 |
| Any invasive procedure in the previous year** |
||||||||||
| No |
17 |
51 |
1.00 |
- |
- |
- |
1.00 |
- |
- |
- |
| Yes |
10 |
3 |
8.92 |
1.93 |
41.31 |
0.005 |
9.14 |
1.31 |
63.73 |
0.025 |
| Median CD4 cell count previous half year (cells/μl) |
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| 0–199 |
20 |
22 |
1.00 |
- |
- |
- |
1.00 |
- |
- |
- |
| ≥ 200 |
7 |
32 |
0.24 |
0.08 |
0.73 |
0.013 |
0.22 |
0.05 |
1.00 |
0.050 |
| Median Log10HIV plasma viral load (cp/ml) in the previous half year*** |
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| ≤ 2.99 |
9 |
14 |
1.00 |
- |
- |
- |
- |
- |
- |
- |
| ≥ 3 |
17 |
39 |
0.69 |
0.25 |
1.92 |
0.478 |
- |
- |
- |
- |
| Any ARV therapy in previous 6 months |
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| No |
17 |
41 |
1.00 |
- |
- |
- |
- |
- |
- |
- |
| Yes |
10 |
13 |
1.86 |
0.65 |
5.29 |
0.245 |
- |
- |
- |
- |
| Any cotrimoxazole in the previous 4 months |
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| No |
19 |
49 |
1.00 |
- |
- |
- |
- |
- |
- |
- |
| Yes |
8 |
5 |
3.06 |
0.99 |
9.41 |
0.051 |
- |
- |
- |
- |
|
^ CS = clinically significant methicillin-resistant Staphylococcus aureus ^^ 95% confidence intervals § All Estimates are adjusted for age at enrolment (< = 42 years and >42 years of age) * Wald test ** It Includes surgery, dialysis or a permanent indwelling catheter or percutaneous medical device. *** Only 77 patients considered; 2 patients not added up to total for missing values. | ||||||||||
Drapeau et al. BMC Infectious Diseases 2007 7:36 doi:10.1186/1471-2334-7-36 |
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