From cat scratch disease to endocarditis, the possible natural history of Bartonella henselae infection
1 Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille cedex 05, France
2 Service de Cardiologie B, Centre Hospitalier Universitaire de La Timone, Marseille, 247, rue Saint-Pierre, Marseille 13385 Cedex 5, France
3 Service de Chirurgie Cardiaque, Centre Hospitalier Universitaire de La Timone, 247, rue Saint-Pierre, Marseille 13385 Cedex 5, France
BMC Infectious Diseases 2007, 7:30 doi:10.1186/1471-2334-7-30Published: 18 April 2007
Most patients with infectious endocarditis (IE) due to Bartonella henselae have a history of exposure to cats and pre-existing heart valve lesions. To date, none of the reported patients have had a history of typical cat scratch disease (CSD) which is also a manifestation of infection with B. henselae.
Here we report the case of a patient who had CSD and six months later developed IE of the mitral valve caused by B. henselae.
Based on this unique case, we speculate that CSD represents the primary-infection of B. henselae and that IE follows in patients with heart valve lesions.