Table 3

In-hospital mortality according to genotype

Genotype

In-hospital mortality (%)

P value


TNF-α (G-308A)

GG

34/182 (19)

GA

20/106 (19)

AA

6/16 (38)

0.19


Il-1β (C3953T)

CC

32/178 (18)

CT

25/117 (21)

TT

5/22 (23)

0.61


PAI-1 (4G/5G)

4G-4G

15/90 (17)

4G-5G

37/183 (20)

5G-5G

11/44 (25)

0.61


uPA (C422T)

CC

40/187 (21)

CT

20/114 (18)

TT

2/12 (17)

0.86


TLR4 (A 896G)

AA

49/274 (18)

AG

8/27 (30)

GG

-

0.11


CD14 (C-159T)

CC

18/92 (20)

CT

33/156 (21)

TT

11/66 (17)

0.90


TNF-α: tumor necrosis factor alpha; Il-1β: interleukin-1 beta; PAI-1: plasminogen activator inhibitor 1; uPA: urokinase-type plasminogen activator; TLR4: toll-like receptor 4; CD14: cluster of differentiation 14; A: adenine; T: thymidine; C: cytosine; G: guanine

Jessen et al. BMC Infectious Diseases 2007 7:108   doi:10.1186/1471-2334-7-108

Open Data