Table 2

Mean difference in hearing level (HL) at baseline and mean change in hearing level associated with variation in baseline plasma HIV RNA and baseline CD4+ T-cell count.*

Baseline Plasma HIV RNA

(Population difference in dB per 10-fold increase)

Baseline CD4+ T-cell count

(Population difference in dB per 100 cells/mL increase)


Baseline HL

Change in HL†

Baseline HL

Change in HL†


Low Frequency PTA‡

-2.3 (-7.9 – 3.2) p = 0.395

-0.016 (-0.93 – 0.90) p = 0.333

0.50 (-1.7 – 2.7) p = 0.646

- 0.27 (-0.86 – 0.31) p = 0.354

High Frequency PTA

-0.44 (-7.9 – 7.0) p = 0.906

0.34 (-1.7 – 2.4) p = 0.747

-0.29 (-2.7 – 2.2) p = 0.801

0.089 (-0.71 – 0.53) p = 0.780


*A negative value indicates improved hearing and a positive value indicates worse hearing

†Adjusted for baseline pure tone average and time since baseline.

‡PTA = Pure Tone Average

Schouten et al. BMC Infectious Diseases 2006 6:28   doi:10.1186/1471-2334-6-28

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