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Surgical wound infection: epidemiology, pathogenesis, diagnosis and management

Robert H Rubin email

Osborne Professor of Health Sciences and Technology and Professor of Medicine, Harvard Medical School, Associate Director of the Division of Infectious Disease, Brigham and Women's Hospital and Director of the Center for Experimental Pharmacology and Therapeutics, Harvard-MIT Division of Health Sciences and Technology; Boston MA, 02115, USA

author email corresponding author email

BMC Infectious Diseases 2006, 6:171doi:10.1186/1471-2334-6-171

Published: 27 November 2006

Abstract

Surgical wound infection remains a significant problem following an operation, although surveillance for such infections remains a challenge exacerbated by early discharge and outpatient surgery. The riskof such infections isdetermined by technical problems with the operation, particularly bleeding, the amount of devitalized tissue created, and the need for drains within the wound, as well as such metabolic factors as obesity and diabetes. Perioperative antibiotic prophylaxis can decrease the incidence of such infections further, but a technically perfect operation is even more important.


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