Table 2

Demographics and clinical characteristics, by co-receptor tropism
FPR Criteria FPR = 10 FPR = 5.75
Patient characteristics CXCR4 (n=44), n (row %) R5 (n=66), n (row %) P-value CXCR4 (n=35), n (row %) R5 (n=75), n (row %) P-value
Median age (median, IQR) 36.9 [28.8–45.4] 36.4 [27.6–44.6] 0.665 39.7 [29.4–45.4] 35.6 [27.6–45.0] 0.539
Male gender 38 (39.1) 59 (61.0) 0.765 30 (30.9) 67 (69.1) 0.752
Ethnicity
Chinese 34 (77.3) 54 (81.8) 0.630 27 (77.1) 61 (81.3) 0.617
Non-Chinese 10 (22.7) 12 (18.2) 8 (22.9) 14 (18.7)
Transmission risk
Heterosexual 20 (45.5) 30 (45.5) 0.945 15 (42.9) 36 (48.0) 0.502
MSM 23 (52.3) 33 (50.0) 14 (40.0) 32 (42.7)
Othersa 1 (3.0) 3 (4.5) 6 (17.1) 7 (9.3)
CD4 count at presentation (median, IQR) 226 [32–402] 333 [200–462] 0.013 219 [35–336] 333 [189–470] 0.025
Evidence of recent seroconversion(n=25)
Subtype B 2 (8.0) 4 (16.0) 0.011 1 (4.0) 5 (20.0) 0.007
CRF01_AE 3 (12.0) 10 (40.0) 3 (12.0) 10 (40.0)
CRF51_01B 5 (2.0) 0 (0.0) 5 (20.0) 0 (0.0)
Othersc 0 (0.0) 1 (4.0) 0 (0.0) 1 (4.0)

Abbreviations: IQR, interquartile range; MSM, men who have sex with men; FPR, false-positive rate.

a Blood transfusion, intravenous drug use (IVDU), bisexual.

b Other subtypes: CRF02_AG, CRF34_01B, CRF07_BC, CRF15_01B.

c Other subtypes: CRF33_01B.

Ng et al.

Ng et al. BMC Infectious Diseases 2013 13:90   doi:10.1186/1471-2334-13-90

Open Data