Table 1

Characteristics of OXA-181-producing Klebsiella pneumoniae clinical isolates
Isolate Hospital Specimen Date of Isolation ST 16S rRNA methylase gene β-lactamases Plasmids MIC (mg/L)
Size (kb) Replicon(s) IMP MEM ETP FOX CTX CAZ AZT COL TGC LEV GEN AMK
KPO8 Hospital A Tracheal aspirate 18/01/2011 17 armA TEM-116, SHV-11, CTX-M-15, OXA-1 ~97, ~170 A/C >32 >32 >32 >256 >256 64 >256 0.125 2 0.25 >256 >256
KPO9 Hospital A Sputum 8/02/2011 17 armA TEM-1, SHV-11, CTX-M-15, OXA-1 ~9, ~150, ~170 A/C >32 >32 >32 >256 >256 64 >256 16 >256 >256 >256 >256
KPO7 Hospital A Tracheal aspirate 9/12/2010 14 armA TEM-1, SHV-1, CTX-M-15, OXA-1, OXA-9 ~1.5, ~50, ~170, ~194 A/C, F >32 >32 >32 >256 >256 >256 >256 0.25 12 >256 >256 >256
KPO26 Hospital A Sputum 14/05/2011 14 ND TEM-1, SHV-1, CTX-M-15, OXA-1, OXA-9 ~1.6, ~194 A/C >32 >32 >32 >256 >256 >256 >256 32 4 >256 >256 96
KPO6916 Hospital A Blood 2/03/2012 14 armA TEM-1, SHV-1, CTX-M-15, OXA-1, OXA-9 ~1.6, ~50, ~170, ~194 A/C 8 8 >32 >256 >256 >256 >256 0.25 16 >256 >256 >256
KPO7431 Hospital B Urine 22/02/2012 14 armA TEM-1, SHV-11, CTX-M-15, OXA-1, OXA-9 ~1.5, ~50, ~170, ~194 A/C, F 4 4 >32 >256 >256 >256 >256 0.25 8 >256 >256 >256
KPO83 Hospital C Urine 30/12/2011 14 armA TEM-1, SHV-1, CTX-M-15, OXA-1, OXA-9 ~170 A/C 32 8 >32 >256 >256 >256 >256 0.5 16 32 >256 >256
KPO9–T armA OXA-181, CTX-M-15 ~170 A/C 2 0.5 0.5 2 3 1 0.75 0.125 0.125 0.002 >256 >256
KPO26 –T ND OXA-181, OXA-9 ~194 A/C 2 0.19 0.25 12 6 2 6 0.125 0.125 0.003 0.125 1
E. coli J53 0.125 0.016 0.04 1 0.064 0.25 0.064 0.125 0.064 0.004 0.125 0.125

Legend:

MIC, minimum inhibitory concentration; IPM, imipenem; MEM, meropenem; ETP, ertapenem; FOX, cefoxitin; CTX, cefotaxime; CAZ, ceftazidime; AZT, aztreonam; COL, colistin; TCG, tigecycline; LEV, levofloxacin; GEN, gentamicin; AMK, amikacin; KPO8, KPO9, KPO7, KPO26, KPO6916, KPO7431, KPO83 carbapenem-resistant K. pneumoniae clinical isolate; KP09-T, KP026-T, K. pneumoniae transconjugant from KP09, KP026; J53, E. coli recipient strain.

Balm et al.

Balm et al. BMC Infectious Diseases 2013 13:58   doi:10.1186/1471-2334-13-58

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