Table 2

Clinical characteristics: comparison of patients with and without asthma (n = 473)
Characteristic Patients with asthma Patients without asthma P-Value*
No. (%) (n = 137) No. (%) (n = 336)
Median days from onset to admission (range) 2 (0 – 20) (n = 136) 3 (0 – 21) (n = 332) 0.06
Admission within 2 days of illness onset 74/136 (54) 150/334 (45) 0.06
Median length of stay- days (range) 3 (0 – 47) (n = 136) 3 (0 – 77) (n = 332) 0.14
Clinical symptoms at admission
 Cough 118 (86) 284 (85) 0.45
 Fever 115 (84) 294 (88) 0.20
 Shortness of Breath 91 (66) 155 (46) <0.01
 Wheezing 62 (45) 47 (14) <0.01
 Fatigue/Weakness 47 (34) 125 (37) 0.71
 Myalgias 43 (31) 122 (36) 0.57
 Rhinorrhea 42 (31) 103 (31) 0.88
 Chills 38 (28) 120 (36) 0.23
 Sore Throat 33 (24) 96 (29) 0.25
 Vomiting 31 (23) 98 (29) 0.08
 Headache 31 (23) 99 (30) 0.17
 Diarrhea 18 (13) 75 (22) 0.03
Underlying medical condition
 Any condition excluding asthma 64 (47) 217 (50) 0.11
 Diabetes 24 (18) 51 (15) 0.18
 Chronic obstructive pulmonary disease 18 (13) 31 (9) 0.04
 Cardiovascular disease 16 (12) 52 (16) 0.55
 Immunosuppression 15 (11) 48 (14) 0.45
 Neuromuscular disorder 11 (8) 26 (8) 0.87
 Cognitive dysfunction 10 (7) 25 (7) 0.76
 Seizure disorder 7 (5) 25 (7) 0.21
 Chronic renal disease 3 (2) 38 (11) <0.01
Pregnancy 8 (6) 38 (12) 0.11
Current smoker 23/121 (19) 58/303 (19) 0.56
Obese or morbidly obese 47/129 (36) 103/298 (35) 0.37
Positive sterile site culture 1/137 (1) 13/336 (4) 0.11
Pneumonia at admission 45/123 (37) 133/281 (47) 0.05
Seasonal flu vaccine 33/86 (38) 64/203 (32) 0.49

*P-Values stratified by age-group.

Body-Mass Index (BMI) was calculated for a subset of patients for whom height and weight were available to determine obesity (BMI 30–39.9 in adults ≥18 years or BMI percentile 95–100 in children 2 to 19 years old) and morbid obesity (BMI ≥40 in adults only); pregnant women were excluded from this calculation.

McKenna et al.

McKenna et al. BMC Infectious Diseases 2013 13:57   doi:10.1186/1471-2334-13-57

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