Table 2

Neisseria gonorrhoeae with decreased susceptibility or resistance to cefixime or ceftriaxone (≥0.125) isolated in Hanoi, Vietnam in 2011 (n = 30)
NG-MAST Minimum inhibitory concentration penA alteration mtrR alteration PorB1b (penB alteration)
Cefixime Ceftriaxone A501 alteration (penA allele [[16]]) A-deletion in promoter region MtrR coding region G101 A102
ST4787 (n = 1) 0.25 0.25 T (XVIII) Yes A39T K D
ST4787 (n = 2) 0.125 0.25 T (XVIII) Yes A39T K D
ST4787 (n = 1) 0.125 0.125 V (A501 New**) Yes H105Y K D
ST4787 (n = 3) 0.064 0.125 T (XVIII) Yes A39T K D
ST4787 (n = 1) 0.032 0.125 T (XVIII) Yes A39T K D
ST7159 (n = 2) 0.064 0.125/0.25 T (XVIII) Yes D79N T86A H105Y K D
ST4676 (n = 1) 0.125 0.25 T (XVIII) Yes H105Y K G
3 STsa (n = 4) 0.125 0.125 T (XVIII) Yes A39T K/Db D/Gb
12 STs (n = 15) 0.064 0.125 T/V/WTc Yes A39T G45D H105Yd K/D/Te D/G/WTe

NG-MAST, Neisseria gonorrhoeae multiantigen sequence typing; ST, sequence type.

a ST7739 (n = 2), ST7160 (n = 1) and ST7741 (n = 1).

b G101D/A102G (n = 2) and G101K/A102D (n = 1).

c A501V New** (n = 9), XVIII (n = 3), XIII (n = 2) and XII (n = 1).

d H105Y (n = 8), A39T (n = 4), and G45D (n = 3).

e G101K/A102D (n = 11), G101D/A102G (n = 2), G101D/WT (n = 1), G101T/A102D (n = 1).

Olsen et al.

Olsen et al. BMC Infectious Diseases 2013 13:40   doi:10.1186/1471-2334-13-40

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