Predicted interaction networks of genes significantly dysregulated in HVL compared to Control. (A) The interactions between genes were identified using STRING software. Colored lines indicate different sources of evidence for each interaction. Circles highlight the predominant clusters within the network. (B & C) Gene Ontology Enrichment analysis for biological processes using significantly differentially regulated genes in LVL and HVL groups in comparison with CT group. Genes that are differentially regulated in LVL group relative to the CT yielded 4 significant terms for biological processes (B), while those that are differentially regulated in HVL with respect to CT yielded 34 (C). Bar graphs are generated using average –lop of p value for each term on y-axis and term name on x-axis. CT, uninfected control; LVL, low viral load group; HVL, high viral load group.
Duskova et al. BMC Infectious Diseases 2013 13:250 doi:10.1186/1471-2334-13-250