A: Expression profile of differentially regulated miRNAs in HIV-1 infected versus uninfected subjects. (A) The Venn diagram displays the number and overlap of significantly differentially expressed miRNA (Benjamini-Hochberg adjusted, p < 0.05) among the LVL and HVL groups relative to the CT and within the infected groups. Hierarchical clustering of miRNA between CT and LVL (B); and CT and HVL (C). MicroRNA in the clustergram are dysregulated at a significance cutoff of p < 0.05. The dendogram depicting the clustering of samples is calculated using Complete linkage with Euclidian distance measure values. Color ranging from green to red indicates minimum to maximum ∆CT. Numbers on X-axis represent subject group. CT, uninfected controls; LVL, low viral load subjects; HVL, high viral load subjects. The clustergrams were generated using StatMiner analyses.
Duskova et al. BMC Infectious Diseases 2013 13:250 doi:10.1186/1471-2334-13-250