Table 1

Characteristics of HIV positive patients who attended King’s College Hospital, London, UK between January 2000 and December 2009
Characteristics at cohort entry1,2 All patients (n = 2751) ICU admission (n = 118) No ICU admission (n = 2633) P value
Age at diagnosis (mean, SD) 35.2 (9.4) 38.4 (9.7) 35.0 (9.3) 0.002
Female sex 1183 (43) 75 (64) 1108 (42) <0.0001
Black ethnicity 1710 (62) 76 (65) 1634 (62) 0.57
HIV exposure risk factor 0.001
Heterosexual 1645 (60) 77 (69) 1568 (60)
Homosexual 739 (27) 22 (20) 717 (27)
IVDU 132 (5) 11 (10) 121 (5)
Hepatitis B surface antigen positive 134 (7) 12 (12) 122 (7) 0.04
Hepatitis C antibody positive 196 (9) 7 (7) 189 (9) 0.54
AIDS diagnosis3 554 (22) 58 (50) 493(19) 0.0001
CD4 cell count (median, IQR) 302 (134, 472) 70 (21, 207) 312 (148, 482) <0.001
Late HIV diagnosis 1410 (59) 96 (89) 1314 (58) <0.0001
Advanced HIV disease 810 (34) 79 (73) 731 (32) <0.0001
Characteristics of ICU patients1,4,5
CD4 cell count (median, IQR) 81 (21, 191)
Receiving cART 47 (39)
HIV RNA <400 c/mL 20 (21)
APACHE2 score (median, IQR) 23 (17, 28)
Opportunistic infection6 54 (46)
Non-opportunistic infection6 19 (16)
Malignancy6 13 (11)
Liver disease6 6 (5)
Neurological disease6 5 (4)
Other6 21 (17)

1 Expressed as N (%) unless otherwise indicated.

2 Within 3 months of cohort entry.

3 See methods for definitions.

4 % are based on number of episodes.

5 At the time of first ICU admission.

6 More than one clinical diagnosis may be recorded.

Shrosbree et al.

Shrosbree et al. BMC Infectious Diseases 2013 13:23   doi:10.1186/1471-2334-13-23

Open Data